(British Approved Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Dihidroergotamina; Dihydroergotamiini; Dihydroergotamin; Dihydroergotaminum BAN: Dihydroergotamine INN: Dihydroergotamine [rINN (en)] INN: Dihidroergotamina [rINN (es)] INN: Dihydroergotamine [rINN (fr)] INN: Dihydroergotaminum [rINN (la)] INN: Дигидроэрготамин [rINN (ru)] Chemical name: (5´S,8R)-5´-Benzyl-9,10-dihydro-12´-hydroxy-2´-methyl-3´,6´,18-trioxoergotaman Molecular formula: C33H37N5O5 =583.7 CAS: 511-12-6 ATC code: N02CA01 Read code: y0CdZ Dihydroergotamine Mesilate (British Approved Name Modified, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: Dihidroergotamin-mezilát; Dihidroergotamina, mesilato de; Dihidroergotamino mesilatas; Dihydroergotamiinimesilaatti; Dihydroergotamin-mesylát; Dihydroergotamine Mesylate; Dihydroergotamine Methanesulphonate; Dihydroergotamini Mesilas; Dihydroergotaminmesilat BAN: Dihydroergotamine Mesilate [BANM] USAN: …
[ Continue Reading... ]Category: Antimigraine
(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: Almotriptán, malato de; LAS-31416 (almotriptan); PNU-180638E (almotriptan malate) BAN: Almotriptan Malate [BANM] USAN: Almotriptan Malate INN: Almotriptan Malate [rINNM (en)] INN: Malato de almotriptán [rINNM (es)] INN: Almotriptan, Malate d’ [rINNM (fr)] INN: Almotriptani Malas [rINNM (la)] INN: Альмотриптана Малат [rINNM (ru)] Chemical name: 1-[({3-[2-(Dimethylamino)ethyl]indol-5-yl}methyl)sulfonyl]pyrrolidine malate (1:1) Molecular formula: C17H25N3O2S,C4H6O5 =469.6 CAS: 154323-57-6 (almotriptan); 181183-52-8 (almotriptan malate) ATC code: N02CC05 Adverse Effects and Precautions As for Sumatriptan. Almotriptan should not be used in patients with severe hepatic impairment since clearance is likely to be …
[ Continue Reading... ]Brand Name: Axert Active Ingredient: almotriptan malate Indication: Treatment of acute migraine headache in adults Company Name: Pharmacia & Upjohn Availability: NDA filed with FDA on December 17, 1999 Axert: Introduction During a migraine headache attack, changes in brain activity induce inflammation of blood vessels and nerves in the head. Attacks may be triggered by alcohol, certain foods, too much or too little sleep, menstruation, emotional stress, or environmental factors. The “triptan” family of drugs, which bind to serotonin receptors in the brain, is currently the most effective class of agents for treating migraine headache. Sumatriptan (Imitrex, manufactured by Glaxo Wellcome) was the …
[ Continue Reading... ]Synthesizing the results of three previous studies, researchers from the Headache Care Center in Springfield, Missouri, concluded that one 2.5 mg dose of zolmitriptan (Zomig) may provide long-term relief from migraines. The findings, which were presented at the Diamond Headache Clinic’s Headache Update `99, analyze the compiled data of three different studies. Each study compared groups of participants that took either zolmitriptan (Zomig) or a placebo, though no one knew which pill they were taking. The studies show that migraines most often occur between six and seven in the morning when people are getting ready for work and school. Taking the medication between 6 and 9 a.m. provided headache relief for …
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