Category: Muscle relaxants

Few Muscle Relaxants

Afloqualone Drug Nomenclature Synonyms: Aflocualona; HQ-495 INN: Afloqualone [rINN (en)] INN: Aflocualona [rINN (es)] INN: Afloqualone [rINN (fr)] INN: Afloqualonum [rINN (la)] INN: Афлоквалон [rINN (ru)] Chemical name: 6-Amino-2-fluoromethyl-3-o-tolylquinazolin-4(3H)-one Molecular formula: C16H14FN3O =283.3 CAS: 56287-74-2 Pharmacopoeias. In Japan. Profile Afloqualone is a centrally acting skeletal muscle relaxant that has been given orally for the treatment of muscle spasm associated with musculoskeletal conditions. Photosensitivity reactions have been reported. Eperisone Hydrochloride Drug Nomenclature INN: Eperisone Hydrochloride [rINNM (en)] INN: Hidrocloruro de eperisona [rINNM (es)] …

[ Continue Reading... ]

Tizanidine Hydrochloride

(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: AN-021; DS-103-282; DS-103-282-ch; Tizanidina, hidrocloruro de BAN: Tizanidine Hydrochloride [BANM] USAN: Tizanidine Hydrochloride INN: Tizanidine Hydrochloride [rINNM (en)] INN: Hidrocloruro de tizanidina [rINNM (es)] INN: Tizanidine, Chlorhydrate de [rINNM (fr)] INN: Tizanidini Hydrochloridum [rINNM (la)] INN: Тизанидина Гидрохлорид [rINNM (ru)] Chemical name: 5-Chloro-N-(2-imidazolin-2-yl)-2,1,3-benzothiadiazol-4-ylamine hydrochloride Molecular formula: C9H8ClN5S,HCl =290.2 CAS: 51322-75-9 (tizanidine); 64461-82-1 (tizanidine hydrochloride) ATC code: M03BX02 Pharmacopoeias. In Japan and US. The United States Pharmacopeia 31, 2008, and Supplements 1 and 2 (Tizanidine Hydrochloride). Store in airtight containers. Adverse Effects and Precautions Tizanidine …

[ Continue Reading... ]

Methocarbamol

(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Guaiphenesin Carbamate; Methocarbamolum; Metocarbamol; Metokarbamol; Metokarbamoli BAN: Methocarbamol INN: Methocarbamol [rINN (en)] INN: Metocarbamol [rINN (es)] INN: Méthocarbamol [rINN (fr)] INN: Methocarbamolum [rINN (la)] INN: Метокарбамол [rINN (ru)] Chemical name: 2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate Molecular formula: C11H15NO5 =241.2 CAS: 532-03-6 ATC code: M03BA03 Read code: y031u Pharmacopoeias. In US. The United States Pharmacopeia 31, 2008, and Supplements 1 and 2 (Methocarbamol). A white powder, odourless or having a slight characteristic odour. M.p. about 94° or, if previously ground to a fine powder, about 90°. Soluble 1 …

[ Continue Reading... ]

Dantrolene Sodium

(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: Dantroleno sódico; F-368 (dantrolene); F-440 BAN: Dantrolene Sodium [BANM] USAN: Dantrolene Sodium INN: Dantrolene Sodium [rINNM (en)] INN: Dantroleno sódico [rINNM (es)] INN: Dantrolène Sodique [rINNM (fr)] INN: Natrii Dantrolenum [rINNM (la)] INN: Натрий Дантролен [rINNM (ru)] Chemical name: The hemiheptahydrate of the sodium salt of 1-[5-(4-nitrophenyl)furfurylideneamino]imidazolidine-2,4-dione Molecular formula: C14H9N4NaO5,31/2H2O =399.3 CAS: 7261-97-4 (dantrolene); 14663-23-1 (anhydrous dantrolene sodium); 24868-20-0 (dantrolene sodium, hemiheptahydrate) ATC code: M03CA01 Read code: y031p [Musculoskeletal Use]; y03KP [Anaesthesia] Pharmacopoeias. In British, Japan, and US. British Pharmacopoeia 2008 (Dantrolene Sodium). A yellowish-orange to …

[ Continue Reading... ]

Cyclobenzaprine Hydrochloride

( US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: Ciclobenzaprina, hidrocloruro de; MK-130 (cyclobenzaprine); Proheptatriene Hydrochloride; RP-9715 (cyclobenzaprine); Ro-4-1557 (cyclobenzaprine) USAN: Cyclobenzaprine Hydrochloride INN: Cyclobenzaprine Hydrochloride [rINNM (en)] INN: Hidrocloruro de ciclobenzaprina [rINNM (es)] INN: Cyclobenzaprine, Chlorhydrate de [rINNM (fr)] INN: Cyclobenzaprini Hydrochloridum [rINNM (la)] INN: Циклобензаприна Гидрохлорид [rINNM (ru)] Chemical name: 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-NN-dimethylpropylamine hydrochloride Molecular formula: C20H21N,HCl =311.8 CAS: 303-53-7 (cyclobenzaprine); 6202-23-9 (cyclobenzaprine hydrochloride) ATC code: M03BX08 Note. The following terms have been used as ‘street names’ or slang names for various forms of cyclobenzaprine hydrochloride: Cyclo; Cyclone. Pharmacopoeias. In US. The United States Pharmacopeia …

[ Continue Reading... ]

Muscle Relaxants

The muscle relaxants included in this chapter are used in the management of musculoskeletal and neuromuscular disorders. There are 2 main types: • centrally acting relaxants — these generally have a selective action on the CNS and are principally used for relieving painful muscle spasms or spasticity occurring in musculoskeletal and neuromuscular disorders. Their mechanism of action may be due to their CNS-depressant activity. Baclofen and tizanidine are two examples. • directly acting relaxants — dantrolene is a drug that has a direct action on skeletal muscle and is used for the relief of spasticity associated with a variety of conditions. Also included in this chapter are botulinum toxins A and …

[ Continue Reading... ]

Chlorzoxazone

(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): (British Approved Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Chlorobenzoxazolinone; Chlorzoxazonum; Clorzoxazona; Klooritsoksatsoni; Klorzoxazon BAN: Chlorzoxazone INN: Chlorzoxazone [rINN (en)] INN: Clorzoxazona [rINN (es)] INN: Chlorzoxazone [rINN (fr)] INN: Chlorzoxazonum [rINN (la)] INN: Хлорзоксазон [rINN (ru)] Chemical name: 5-Chlorobenzoxazol-2(3H)-one Molecular formula: C7H4ClNO2 =169.6 CAS: 95-25-0 ATC code: M03BB03 Pharmacopoeias. In US. The United States Pharmacopeia 31, 2008, and Supplements 1 and 2 (Chlorzoxazone). A white or practically white, practically odourless, crystalline powder. Slightly …

[ Continue Reading... ]

Chlorphenesin Carbamate

(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): (British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: Clorfenesina, carbamato de; U-19646 BAN: Chlorphenesin Carbamate [BANM] USAN: Chlorphenesin Carbamate INN: Chlorphenesin Carbamate [pINNM (en)] INN: Carbamato de clorfenesina [pINNM (es)] INN: Chlorphénésine, Carbamate de [pINNM (fr)] INN: Chlorphenesini Carbamatum [pINNM (la)] INN: Хлорфенезина Карбамат [pINNM (ru)] Chemical name: 3-(4-Chlorophenoxy)propane-1,2-diol 1-carbamate Molecular formula: C10H12ClNO4 =245.7 CAS: 104-29-0 (chlorphenesin); 886-74-8 (chlorphenesin carbamate) Pharmacopoeias. In Japan. Adverse Effects and Precautions Chlorphenesin carbamate produces drowsiness and dizziness. …

[ Continue Reading... ]

Carisoprodol

(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish):(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): (British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Carisoprodol; Carisoprodolum; Isopropylmeprobamate; Karisoprodol; Karisoprodoli; Karizoprodol; Karizoprodolis BAN: Carisoprodol INN: Carisoprodol [rINN (en)] INN: Carisoprodol [rINN (es)] INN: Carisoprodol [rINN (fr)] INN: Carisoprodolum [rINN (la)] INN: Каризопродол [rINN (ru)] Chemical name: 2-Methyl-2-propyltrimethylene carbamate isopropylcarbamate Molecular formula: …

[ Continue Reading... ]

Botulinum Toxins

Toxinas botulfnicas. ATC — M03AX01. ATC Vet — QM03AX01. Description. Botulinum toxins A and B are neurotoxins produced by Clostridium botulinum. They are proteins comprising a heavy chain thought to be responsible for binding to the target cells and translocation of the toxin across the cell membrane, linked by a disulfide bond to a light chain responsible for the toxic activity. Botulinum A Toxin Botuliinitoksiini tyyppi A; Botulinum A Toksini; Toxin typ A mot botulism; Toxina botulfnica A; Toxine botulinique type A; Toxinum botulinicum typum A. Pharmacopoeias. Europe includes the injection. European Pharmacopoeia, 6th ed., 2008 and Supplements 6.1 …

[ Continue Reading... ]