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• Drugs

  • Antimigraine Drugs
    Cluster headache Medication-overuse headache Migraine Post-dural puncture headache Tension-type headache This post reviews the management of headache, in particular migraine and cluster headache, and the drugs used mainly for their treatment. The mechanisms of head pain or headache [...]
  • Rizatriptan Benzoate
    (British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: MK-0462; MK-462; Rizatriptán, benzoato de BAN: Rizatriptan Benzoate [BANM] USAN: Rizatriptan Benzoate INN: Rizatriptan Benzoate [pINNM (en)] INN: Benzoato de [...]
  • Pizotifen
    (British Approved Name, rINN) Drug Nomenclature Synonyms: BC-105; Pitsotifeeni; Pizotifen; Pizotifeno; Pizotifenum BAN: Pizotifen USAN: Pizotyline INN: Pizotifen [rINN (en)] INN: Pizotifeno [rINN (es)] INN: Pizotifène [rINN (fr)] INN: Pizotifenum [rINN (la)] INN: Пизотифен [rINN (ru)] Chemical name: 9,10-Dihydro-4-(1-methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene Molecular formula: C19H21NS =295.4 CAS: [...]
  • Naratriptan Hydrochloride
    (British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: GR-85548A; GR-85548X (naratriptan); Naratriptán, hidrocloruro de BAN: Naratriptan Hydrochloride [BANM] USAN: Naratriptan Hydrochloride INN: Naratriptan Hydrochloride [rINNM (en)] INN: [...]
  • Methysergide
    (British Approved Name, US Adopted Name, rINN) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: 1-Methyl-d-lysergic Acid Butanolamide; Methysergidum; Metysergid; Metysergidi BAN: Methysergide USAN: Methysergide INN: Methysergide [rINN (en)] INN: Metisergida [rINN (es)] INN: Méthysergide [rINN [...]
  • More from Drugs

• Diagnosis and Therapy

  • Case: Muscarinic cholinomimetic agents. Questions – Answers
    Questions [1] A 62-year-old woman is noted to have open-angle glaucoma. She inadvertently applies excessive pilocarpine to her eyes. This may result in which of the following? A. Bronchial smooth muscle dilation B. Decreased gastrointestinal motility C. [...]
  • Case: Muscarinic cholinomimetic agents. Class
    The efferent nerves of the parasympathetic autonomic nervous system release the neurotransmitter ACh at both preganglionic and postganglionic (i.e., “cholinergic”) nerve endings, and also at somatic nerve endings. Nitric oxide is a cotransmitter [...]
  • Case: Muscarinic cholinomimetic agents
    A 61-year-old man is noted to have increased intraocular pressure on a routine eye examination. The visual acuity is normal in both eyes. The dilated eye examination reveals no evidence of optic nerve [...]
  • Drugs of abuse. Class
    In addition to alcohol, the major drugs of abuse are nicotine, marijuana (∆9-tetrahydrocannabinol), heroin, and the CNS stimulants, notably cocaine and amphetamine and its derivatives (Table Drugs of abuse). Table: Drugs of abuse NICOTINE MARIJUANA COCAINE/AMPHETAMINE Route [...]
  • Drugs of abuse
    A 50-year-old salesman was admitted to the hospital with acute appendicitis. He has no significant medical history, takes no medications, does not smoke cigarettes, and has an alcoholic beverage “once in a while [...]
  • More from Diagnosis and Therapy

• Drug Therapy

  • Lithium
    A 29-year-old man is brought to the emergency center in a drunken stupor. He is accompanied by his wife, who states that he hasn’t been himself at all for the past few months. [...]
  • Antiarrhythmic drugs
    A 62-year-old man is being managed in the intensive care unit following a large anterior wall MI. He has been appropriately managed with oxygen, aspirin, nitrates, and P-adrenergic receptor blockers but has developed [...]
  • Acute Mountain Sickness
    Rapid ascension and exposure to altitudes greater than 8,000 feet without appropriate acclimatization is an environmental malady risked by many outdoors enthusiasts. Initiating within 1 to 2 days, this spectrum of symptoms has [...]