What is Actos?
Pioglitazone (brand name Actos) is an oral antidiabetic agent used in the management of type 2 diabetes mellitus. It belongs to the thiazolidinedione class of medications and works by increasing insulin sensitivity, which helps improve glycemic control in patients with insulin resistance. By activating peroxisome proliferator-activated receptor gamma (PPARγ), Pioglitazone enhances glucose uptake in peripheral tissues, thereby reducing blood glucose levels.
What is Actos used for?
Actos (pioglitazone) is an oral antidiabetic agent that belongs to the thiazolidinedione class of medications. It is used in the treatment of type 2 diabetes mellitus, either as monotherapy or in combination with other medications such as metformin, sulfonylureas, or insulin.
Actos works by activating the peroxisome proliferator-activated receptor gamma (PPAR-gamma) receptors found throughout the body. This activation leads to improved glucose uptake and utilization by muscles, adipose tissue, and liver cells, resulting in lower blood sugar levels. Pioglitazone also has a modest effect on reducing insulin resistance and increasing insulin sensitivity, further contributing to its antidiabetic effects.
In patients with type 2 diabetes, Actos is typically administered once daily, either alone or as part of a multi-drug regimen. It should be used in conjunction with diet and exercise to manage blood sugar levels effectively. Patients initiating treatment with pioglitazone may experience improvements in glycemic control, which can also contribute to the reduction of microvascular complications associated with diabetes. However, the medication’s use must be carefully weighed against its potential risks, such as fluid retention and increased risk of bladder cancer, making regular monitoring essential.
Actos side effects
- Weight gain
- Headache
- Muscle pain
- Diarrhea
- Nausea
- Stomach upset
- Dizziness
- Flu-like symptoms
- Joint pain
- Increased risk of bladder cancer
- Upper respiratory tract infection
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.