What is Amlodipine-candesartan?
Amlodipine-candesartan, also known as Amturnide, is an oral antihypertensive combination medication. It combines the calcium channel blocker amlodipine besylate with the angiotensin II receptor antagonist candesartan cilexetil. Amlodipine works by relaxing blood vessels to improve blood flow and lower blood pressure, while candesartan helps reduce blood pressure by blocking the action of certain hormones that constrict blood vessels. This combination medication is used to treat high blood pressure in adults, and its use is indicated when amlodipine or candesartan are not effective alone as monotherapy.
What is Amlodipine-candesartan used for?
Amlodipine-Candesartan is a fixed-dose combination medication that combines the properties of an angiotensin II receptor antagonist (candesartan) and a calcium channel blocker (amlodipine). It belongs to a class of medications known as ARBs (Angiotensin Receptor Blockers) combined with CCBs (Calcium Channel Blockers), which are used in the management of hypertension.
Amlodipine is a dihydropyridine-type calcium channel blocker that works by relaxing blood vessels, thereby reducing the pressure inside them. This allows for better blood flow and reduced risk of heart-related problems. Candesartan, on the other hand, is an angiotensin II receptor antagonist that blocks the action of angiotensin II, a potent vasoconstrictor hormone that constricts blood vessels. By blocking its effects, candesartan lowers blood pressure and reduces strain on the heart.
When used together as Amlodipine-Candesartan, these two drugs have been shown to be more effective in reducing systolic and diastolic blood pressure compared to either drug alone. The fixed-dose combination of amlodipine-candesartan is often prescribed for patients with hypertension who are at risk of developing cardiovascular diseases, including heart failure, coronary artery disease, or stroke.
Amlodipine-candesartan side effects
- Abdominal pain
- Allergic reactions (such as hives or itching)
- Back pain
- Coughing up blood
- Dizziness
- Fast heart rate
- High blood pressure in children with kidney disease
- Hiccups
- Low potassium levels
- Nosebleeds
- Skin rash
- Swelling of the hands, feet, ankles, face, lips, eyes, throat, or tongue
- Tiredness
- Urinating less than usual
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