What is Amlodipine-felodipine?
Amlodipine and Felodipine are calcium channel blockers (CCBs) used together in fixed-dose combinations, primarily indicated for the treatment of hypertension and angina pectoris. Amlodipine is a dihydropyridine CCB with vasodilatory effects, while felodipine also has dihydropyridine-class properties, providing additive blood pressure-lowering benefits when co-administered. This combination aims to offer improved blood pressure control and/or increased efficacy for managing angina symptoms in eligible patients.
What is Amlodipine-felodipine used for?
Amlodipine belongs to the class of medications known as calcium channel blockers (CCBs). It works by relaxing blood vessels so that blood can flow more easily and increase oxygen delivery to different parts of the body. As a result, it helps to control high blood pressure and angina symptoms. Amlodipine is often prescribed in combination with other antihypertensive medications or as monotherapy for patients diagnosed with essential hypertension.
The efficacy and safety of amlodipine have been extensively studied across various age groups, including children and the elderly. When used alone or combined with other drugs, it has shown significant benefits in lowering diastolic blood pressure levels without excessively decreasing systolic pressure. Additionally, clinical trials have demonstrated that Amlodipine’s primary pharmacological action is due to its ability to decrease peripheral vascular resistance.
Amlodipine-felodipine side effects
• Edema • Dizziness • Headache • Flushing • Fatigue • Chest pain • Back pain • Muscle weakness • Tinnitus (ringing in the ears) • Palpitations • Cold sweats • Confusion • Memory loss • Nausea • Vomiting • Diarrhea • Abdominal pain • Constipation • Rapid or slow heart rate • Increased blood sugar levels • Changes in vision (blurred, double, or distorted) • Muscle cramps • Weight gain or loss • Skin rash or itching • Hair loss
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