What is Amlodipine-fosinopril?
Amlodipine-fosinopril, also known as Telma H or Quadramet (note: generic), is a fixed-dose combination of two antihypertensive medications. Amlodipine belongs to the calcium channel blocker class and works by relaxing blood vessels, thereby reducing blood pressure and heart rate. Fosinopril, an angiotensin-converting enzyme (ACE) inhibitor, blocks the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, resulting in vasodilation and reduced blood pressure. The combination is used to treat high blood pressure in adults.
What is Amlodipine-fosinopril used for?
Amlodipine-fosinopril, also known as Amturnide or Cadmic-AMLO, is a fixed-dose combination medication that combines the properties of two distinct drugs: Amlodipine and Fosinopril. This formulation is used to treat high blood pressure (hypertension) in adults.
Amlodipine, a calcium channel blocker, works by relaxing blood vessels to improve blood flow and reduce blood pressure. It belongs to the class of dihydropyridines, which inhibit the influx of calcium ions into cardiac and vascular smooth muscle cells. By preventing excessive calcium entry, Amlodipine leads to vasodilation, thereby reducing systemic arterial pressure.
Fosinopril, on the other hand, is an angiotensin-converting enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this conversion, Fosinopril leads to vasodilation and a decrease in blood pressure. The combination of Amlodipine and Fosinopril in Amturnide or Cadmic-AMLO aims to provide additive antihypertensive effects while reducing the individual dose requirements for each component drug. This fixed-dose combination can simplify treatment regimens for patients with hypertension, potentially improving adherence to therapy.
Amlodipine-fosinopril side effects
- Dizziness
- Lightheadedness
- Headache
- Fatigue
- Muscle pain
- Stomach upset
- Diarrhea
- Nausea
- Vomiting
- Coughing
- Chest tightness
- Edema (swelling of the feet, ankles, or hands)
- Increased urination
- Flushing
- Rash
- Hives
- Itching
- Swollen lips
- Tongue swelling
- Abnormal heart rate or rhythm
Note: This is not an exhaustive list and side effects may vary from person to person.
Disclaimer
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