What is Amlodipine-furosemide?
Amlodipine-Furosemide (a fixed-dose combination) is a medication used to treat hypertension and heart failure. Amlodipine, an L-type calcium channel blocker, works by relaxing blood vessels to lower blood pressure, while Furosemide, a loop diuretic, increases urine production to also help reduce fluid build-up in the body.
What is Amlodipine-furosemide used for?
Amlodipine-furosemide, also known as a fixed-dose combination of Amlodipine and Furosemide, is a medication used to treat high blood pressure (hypertension) in adults. This antihypertensive drug combines the effects of Amlodipine, a calcium channel blocker, with those of Furosemide, a loop diuretic.
The addition of Furosemide to Amlodipine enhances the therapeutic efficacy and provides a more comprehensive approach to managing hypertension by promoting fluid excretion in combination with vasodilation. This dual-action mechanism is particularly beneficial for patients with resistant or refractory hypertension. Amlodipine-furosemide helps lower blood pressure, reduce cardiac workload, and decrease peripheral vascular resistance. The resulting effect is an improvement in overall cardiovascular health, thereby reducing the risk of associated complications such as heart failure, stroke, and renal disease.
As a fixed-dose combination, Amlodipine-furosemide offers a convenient dosing regimen for patients, streamlining their treatment experience while potentially increasing compliance rates. This formulation has been studied extensively in clinical trials to ensure its safety and efficacy, and it is usually available as tablets or capsules for oral administration. When prescribed by a healthcare provider, Amlodipine-furosemide should be used exactly as directed to achieve optimal therapeutic results and minimize potential adverse effects.
Amlodipine-furosemide side effects
- Edema
- Dizziness
- Nausea
- Headache
- Flushing
- Weakness
- Insomnia
- Diarrhea
- Abdominal pain
- Tachycardia
- Palpitations
- Fatigue
- Muscle cramps
- Hypotension (low blood pressure)
- Elevated potassium levels
- Constipation
- Weight gain or loss
- Skin rash
- Joint pain
- Increased risk of MI and angina
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