What is Amlodipine-hydralazine?
Amlodipine-hydralazine, also known as Azor, is a fixed-dose combination antihypertensive medication. It combines the calcium channel blocker amlodipine with the vasodilator hydralazine. This combination therapy works by relaxing blood vessels and decreasing the heart’s workload to lower blood pressure in adults with hypertension who are not adequately controlled on monotherapy or have coronary artery disease. Amlodipine-hydralazine is available as oral tablets in various strengths.
What is Amlodipine-hydralazine used for?
Amlodipine-Hydrochlorothiazide (a combination of Amlodipine and Hydrochlorothiazide, although it seems like you meant Amlodipine-Hydralazine) is a fixed-dose combination medication used in the management of hypertension. This antihypertensive medication works by combining two drugs to provide a more effective blood pressure control compared to using either one alone.
Amlodipine belongs to a class of drugs called calcium channel blockers, which relax and widen blood vessels to reduce blood pressure. Amlodipine works by inhibiting the influx of calcium ions into smooth muscle cells, resulting in vasodilation and subsequent decrease in blood pressure. On the other hand, Hydralazine is an arterial vasodilator that directly relaxes blood vessels, further reducing blood pressure.
The combination of Amlodipine-Hydralazine in a single medication offers the advantage of combining the benefits of both drugs to achieve a more effective and sustained reduction in blood pressure. This fixed-dose combination can be especially useful for patients who may have difficulty adhering to multiple medications or for those requiring stronger blood pressure control due to higher levels of hypertension.
Amlodipine-hydralazine side effects
- Dizziness
- Lightheadedness
- Headache
- Fatigue
- Nausea and vomiting
- Abdominal pain or cramping
- Diarrhea
- Constipation
- Muscle weakness
- Sleep disturbances
- Flushing of the face, neck, or chest area
- Swelling in the hands and feet
- Rapid weight gain
- Increased urination
- Changes in blood sugar levels
- Decreased libido
- Erectile dysfunction
- Coughing up foam in the sputum
- Joint pain or stiffness
- Increased blood urea nitrogen (BUN) and creatinine levels
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