What is Amlodipine-lisinopril?
Amlodipine-Lisinopril, also known as Amlodipine and Lisinopril combination. This medication is an antihypertensive agent that combines the properties of a calcium channel blocker (amlodipine) with an angiotensin-converting enzyme (ACE) inhibitor (lisinopril). It works by relaxing blood vessels, lowering blood pressure, and reducing fluid buildup in the body. Amlodipine-Lisinopril is primarily used to treat high blood pressure (hypertension), heart failure, and diabetic kidney disease.
What is Amlodipine-lisinopril used for?
Amlodipine-lisinopril is a fixed-dose combination medication consisting of two antihypertensive drugs: amlodipine and lisinopril. Amlodipine, a calcium channel blocker, belongs to the class of dihydropyridines. It works by relaxing blood vessels and reducing blood pressure in individuals with hypertension or coronary artery disease.
Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat high blood pressure and heart failure. By inhibiting the conversion of angiotensin I to angiotensin II, lisinopril causes vasodilation, which reduces peripheral resistance and decreases blood pressure. The combination of amlodipine and lisinopril has been designed to provide additive effects in lowering blood pressure, as well as beneficial effects on heart function and cardiovascular outcomes. This fixed-dose combination has become an important therapeutic option for managing hypertension and reducing the risk of cardiovascular events.
The combination therapy offers several advantages over individual monotherapies, including increased efficacy in controlling high blood pressure, improved tolerability, and enhanced convenience for patients with multiple comorbidities. Clinical studies have demonstrated that amlodipine-lisinopril is effective in lowering systolic and diastolic blood pressures, reducing the incidence of cardiovascular events, such as myocardial infarction and stroke, and improving quality of life for patients with hypertension or heart failure.
Amlodipine-lisinopril side effects
• Dizziness • Headache • Cough • Fatigue • Nausea • Diarrhea • Abdominal pain • Muscle cramps • Vascular issues (such as swelling in hands or feet) • Hyperkalemia (elevated potassium levels) • Hypotension (low blood pressure) • Increased risk of hypoglycemia (low blood sugar) when used with diabetes medications
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