Amlodipine-prazosin

What is Amlodipine-prazosin?

Amlodipine is a calcium channel blocker used to treat high blood pressure and chest pain (angina), while Prazosin is an alpha-1 adrenergic receptor antagonist used to treat high blood pressure, prostate enlargement (BPH), and erectile dysfunction.

What is Amlodipine-prazosin used for?

Amlodipine

Amlodipine is a calcium channel blocker (CCB) medication used to treat high blood pressure and angina. It works by relaxing the muscles in the heart and blood vessels, allowing them to widen and improve blood flow. This increases oxygen supply to the heart and lowers blood pressure. Amlodipine belongs to the dihydropyridine class of CCBs and is commonly used as a first-line treatment for hypertension.

Amlodipine has a long duration of action, typically lasting 24 hours, which allows for once-daily dosing. It may be prescribed alone or in combination with other medications to manage high blood pressure or symptoms of angina. Amlodipine is available in various strengths and formulations, including oral tablets and extended-release capsules.

Prazosin

Prazosin is an alpha-1 adrenergic receptor blocker medication primarily used to treat benign prostatic hyperplasia (BPH) symptoms and high blood pressure. It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate. Prazosin also blocks the action of certain hormones that can cause blood vessels to constrict, thereby lowering blood pressure.

Prazosin has been used for many years as a monotherapy or combination therapy for BPH symptoms. It is usually taken once or twice daily before bedtime to minimize potential dizziness and orthostatic hypotension. Prazosin may be prescribed alone or in combination with other medications, such as diuretics or calcium channel blockers, to manage hypertension or BPH symptoms.

Amlodipine-prazosin side effects

• Dizziness • Headache • Fatigue • Nausea • Diarrhea • Stomach upset • Increased risk of low blood pressure (hypotension) • Rapid or pounding heartbeat (palpitations) • Chest pain or discomfort • Weakness or tiredness • Allergic reactions (rare) • Muscle cramps • Constipation • Weight gain


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