What is Amlodipine-terazosin?
Amlodipine and terazosin combination contains Amlodipine, a calcium channel blocker, and Terazosin, an alpha-1 adrenergic receptor antagonist. It is used to treat high blood pressure and benign prostatic hyperplasia (BPH). Amlodipine works by relaxing the muscles in blood vessel walls, causing the vessels to widen and lowering blood pressure. Terazosin helps to relax the muscles in the prostate and bladder neck, making it easier to urinate. The combination of both medications is used to treat symptoms associated with high blood pressure and BPH, such as difficulty starting or stopping urine flow.
What is Amlodipine-terazosin used for?
Name: Amlodipine-Terazosin Combination.
The amlodipine-terazosin combination, also known as a fixed-dose combination of these two medications, is designed to provide simultaneous blood pressure lowering and symptomatic relief from benign prostatic hyperplasia (BPH) symptoms. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and consequently lowered systemic arterial pressure.
Terazosin, on the other hand, belongs to the alpha-1 adrenergic receptor antagonist class. It functions by relaxing the smooth muscles in the prostate and bladder neck, which allows for improved urine flow and reduced symptoms associated with BPH such as urinary frequency, urgency, and nocturia. The fixed-dose combination of amlodipine and terazosin aims to address both hypertension and BPH simultaneously, potentially reducing the overall burden on patients by simplifying their medication regimen and providing improved symptom relief.
When used together, the expected benefits include lowered blood pressure in hypertensive patients while also alleviating symptoms related to benign prostatic hyperplasia. This combination has been investigated for its efficacy and safety in clinical trials and is typically reserved for patients who have hypertension along with BPH symptoms that do not respond adequately to monotherapy.
Amlodipine-terazosin side effects
- Dizziness
- Lightheadedness
- Orthostatic hypotension
- Syncope
- Headache
- Fatigue
- Weakness
- Muscle cramp
- Diarrhea
- Abdominal pain
- Nausea
- Vomiting
- Increased urination
- Decreased libido
- Erectile dysfunction
- Ejaculation disorder
- Anxiety
- Depression
- Insomnia
- Rash
- Swelling in the legs and ankles (edema)
- Muscle pain
- Joint pain
- Back pain
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