Ampicillin-sulbactam

What is Ampicillin-sulbactam?

Ampicillin-Sulbactam is an antibiotic medication that combines ampicillin, a broad-spectrum penicillinase-sensitive beta-lactam antibiotic, with sulbactam, a penicillinase inhibitor. This combination allows the antibiotic to be more effective against bacteria that produce beta-lactamases and provides coverage for infections caused by susceptible Gram-positive and Gram-negative organisms. It is typically administered intravenously or orally in the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections.

What is Ampicillin-sulbactam used for?

Ampicillin-sulbactam, also known as Unasyn, is a broad-spectrum antibiotic medication that combines the properties of ampicillin and sulbactam. Ampicillin is a penicillinase-resistant beta-lactam antibiotic that belongs to the class of penicillins, while sulbactam is an inhibitor of bacterial beta-lactamases.

The combination of ampicillin-sulbactam provides a synergistic effect that enhances its antibacterial activity and protects it from degradation by bacteria. This makes it effective against a wide range of gram-positive and gram-negative bacteria, including those resistant to other antibiotics. Ampicillin-sulbactam is commonly used to treat various infections such as pneumonia, skin infections, urinary tract infections, and septicemia. It works by inhibiting the synthesis of bacterial cell walls, ultimately leading to bacterial death.

Ampicillin-sulbactam side effects

  • Abdominal or stomach cramps
  • Bloating
  • Chills
  • Cough
  • Diarrhea
  • Dizziness
  • Fever
  • Gas
  • Headache
  • Hearing loss (temporary)
  • Itching
  • Nausea
  • Painful urination
  • Redness of the skin (hives)
  • Rupture of a tendon or muscle
  • Sensitivity to sunlight
  • Stomach pain
  • Tenderness around the anus
  • Vaginal itching or discharge

Disclaimer

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