What is Balofloxacin?
Balofloxacin is a fluoroquinolone antibiotic used in veterinary medicine, particularly for the treatment of respiratory tract infections caused by certain bacterial pathogens. It works by inhibiting DNA gyrase and topoisomerase IV enzymes, which are essential for bacterial DNA replication and transcription. Balofloxacin has been approved for use in dogs, cats, and other small animals to address infections caused by organisms such as Pasteurella multocida and Escherichia coli.
What is Balofloxacin used for?
Balofloxacin is a fluoroquinolone antibiotic that belongs to the second-generation of quinolones. It was initially developed and investigated in China during the 1990s. Balofloxacin has been marketed for various indications, including respiratory tract infections, skin and soft tissue infections, urinary tract infections, and more serious conditions such as hospital-acquired pneumonia.
The chemical structure of balofloxacin is similar to that of other fluoroquinolones like ciprofloxacin and levofloxacin. As a result, it possesses broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, including those resistant to other antibiotics. However, like other quinolones, its widespread use has been limited by concerns regarding potential side effects such as phototoxicity and increased risk of tendonitis and tendinitis, particularly in older patients and those with pre-existing medical conditions.
Balofloxacin side effects
- Abnormality in stool
- Diarrhea
- Dizziness
- Hives
- Increased alkaline phosphatase levels
- Infection
- Itching sensation
- Pain or discomfort
- Rash
- Sleepiness
- Stomach cramps
- Tiredness
- Urinary frequency
- Vaginal infection
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