What is Captopril?
Captopril belongs to the class of medications known as angiotensin-converting enzyme (ACE) inhibitors. It is primarily used in the treatment of hypertension, also referred to as high blood pressure. Captopril works by blocking the conversion of angiotensin I into angiotensin II, a potent vasoconstrictor, thus resulting in vasodilation and subsequent decrease in blood pressure. Additionally, captopril has been shown to be beneficial in managing symptoms of congestive heart failure by reducing fluid accumulation in the body and improving cardiac output.
What is Captopril used for?
Captopril is an oral medication belonging to the class of angiotensin-converting enzyme (ACE) inhibitors. It was first introduced in 1981 by Squibb Pharmaceuticals as a tablet formulation, and later developed into various formulations such as capsules, injectables, and solutions for intravenous administration.
The primary use of captopril is to manage hypertension (high blood pressure) and certain types of heart failure. The drug works by selectively inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor in the renin-angiotensin system. By doing so, it causes vasodilation, resulting in reduced peripheral resistance and subsequently lowering blood pressure. In heart failure patients, captopril helps improve cardiac output by reducing afterload, thereby facilitating increased forward flow to the lungs and enhancing exercise tolerance.
Captopril has also been used off-label for treating kidney disease, such as diabetic nephropathy, as it slows the progression of renal impairment in patients with compromised kidney function. Its use is often in conjunction with other medications to achieve optimal blood pressure control or alleviate heart failure symptoms. Overall, captopril’s mechanism and efficacy make it a crucial component of treatment regimens for hypertension and certain cardiovascular conditions.
Captopril side effects
- Dizziness
- Cough
- Diarrhea
- Nausea
- Vomiting
- Headache
- Fatigue
- Muscle cramps
- Rash
- Hives
- Taste changes
- Stomach pain
- Abdominal discomfort
- Chest pain (angina)
- Coughing up blood (hemoptysis)
- Wheezing or shortness of breath
- Lightheadedness
- Drowsiness
- Weakness
- Allergic reactions
Disclaimer
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