What is Cefazedone?
Cefazedone is a second-generation cephalosporin antibiotic that has a broad spectrum of activity against Gram-positive and Gram-negative bacteria. It belongs to the first generation of orally administered cephalosporins, similar to cephalexin. Cefazedone exerts its antibacterial effect by inhibiting cell wall synthesis in susceptible microorganisms. It is used for the treatment of various bacterial infections, including respiratory tract infections, skin and soft tissue infections, and urinary tract infections, but it is not commonly used in many countries due to concerns about resistance development.
What is Cefazedone used for?
Cefazedone is an oral third-generation cephalosporin antibiotic belonging to the 4th generation of cephalosporins, which offers broader bacterial spectrum activity. It was initially developed by Toyo Jozo Co., Ltd and later approved for use in various countries including Japan, France, Italy, Spain, and Turkey.
Cefazedone has a broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, with particular efficacy against Escherichia coli, Klebsiella pneumoniae, and Enterobacter species. This antibiotic is commonly used for the treatment of infections caused by susceptible microorganisms such as respiratory tract infections (including community-acquired pneumonia), urinary tract infections, skin and soft tissue infections, and gynecological infections.
As a third-generation cephalosporin, cefazedone provides resistance to beta-lactamase-producing bacteria. However, it is not recommended for the treatment of patients with known hypersensitivity reactions or allergies to cephalosporins. Cefazedone is administered orally in tablet form and may be associated with side effects such as diarrhea, vomiting, nausea, abdominal pain, and allergic reactions.
Cefazedone side effects
• Diarrhea • Nausea and vomiting • Abdominal pain or discomfort • Headache • Dizziness or lightheadedness • Fatigue • Skin rash or itching • Fever • Injection site reactions (if given intramuscularly) • Increased blood urea nitrogen (BUN) or creatinine levels • Allergic reactions (rare, but serious), which may include symptoms such as: • Hives • Itching • Swelling of the face, lips, tongue, or throat • Difficulty swallowing or breathing • Chest pain or tightness
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.