What is Cefbuperazone?
Cefbuperazone is a third-generation cephalosporin antibiotic effective against a broad spectrum of gram-positive and gram-negative bacteria. It inhibits bacterial cell wall synthesis, leading to cell death. Cefbuperazone has a long elimination half-life, allowing once-daily dosing in some infections.
What is Cefbuperazone used for?
Cefbuperazone is a third-generation cephalosporin antibiotic. It was first synthesized in the 1970s and has been used clinically since then. This drug belongs to the cef-3g category of antibiotics, which is characterized by its broad-spectrum activity against Gram-positive and Gram-negative bacteria. Cefbuperazone has a unique chemical structure that allows it to be effective against a wide range of pathogens, including many species of Staphylococcus and Escherichia.
Cefbuperazone is administered parenterally (intramuscularly or intravenously), and its pharmacokinetic profile is characterized by high bioavailability, low protein binding, and moderate tissue distribution. The drug exerts its antibacterial effect by inhibiting the synthesis of bacterial cell walls through inhibition of transpeptidase enzymes. As a result, Cefbuperazone has been used to treat various infections caused by susceptible pathogens, such as urinary tract infections, skin and soft tissue infections, and respiratory tract infections.
Cefbuperazone side effects
• Abdominal pain • Allergic reactions (rash, hives, itching) • Bloody diarrhea • Cough • Diarrhea • Headache • Increased sensitivity to light • Joint pain or swelling • Muscle pain • Nausea and vomiting • Pain in the arms or legs • Seizure • Swelling of face, lips, tongue, or throat • Vaginal yeast infection • Yellowing of skin or eyes (jaundice)
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