What is Cefixime?
Cefixime is an oral third-generation cephalosporin antibiotic used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, and skin infections. It works by inhibiting cell wall synthesis in susceptible bacteria, ultimately leading to their death or inhibition of growth. Cefixime is available in tablet or powder for suspension formulations. It is typically taken once or twice daily, with food, to enhance absorption and reduce gastrointestinal side effects.
What is Cefixime used for?
Cefixime is an oral, third-generation cephalosporin antibiotic used to treat various bacterial infections. It belongs to the class of antibiotics known as cephems, which inhibit cell wall synthesis in bacteria by binding to penicillin-binding proteins (PBPs). Cefixime exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria.
Clinical Uses
Cefixime is primarily prescribed for treating infections caused by susceptible organisms. Its clinical applications include infections of the upper respiratory tract, skin, urinary tract, and middle ear. The antibiotic is also effective against bacterial pathogens that cause gonorrhea and urethritis in sexually active adults. Cefixime has a unique pharmacokinetic profile, with minimal plasma protein binding and extensive tissue distribution, which allows for its rapid and effective concentration at the site of infection.
Dosage and Administration
Cefixime tablets or suspension are typically taken orally once daily without regard to meals. The dosage form is usually initiated as a single 400mg dose, followed by once-daily administration depending on the patient’s age and the type of infection being treated.
Cefixime side effects
- Abdominal pain
- Allergic reactions (hives, itching, difficulty breathing)
- Diarrhea
- Headache
- Nausea and vomiting
- Rarely: Clostridioides difficile infection
- Seizures
- Stevens-Johnson syndrome
- Vaginitis
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.