What is Cefmatilen?
Cefmatilen is an injectable antibiotic belonging to the third-generation cephalosporin class of drugs. It is used to treat various bacterial infections, particularly those caused by susceptible gram-positive and gram-negative bacteria in adults with moderate to severe renal impairment. Cefmatilen is administered via intravenous infusion and its spectrum of activity includes but is not limited to E. coli, K. pneumoniae, S. aureus, and other similar pathogens.
What is Cefmatilen used for?
Cefmatilen, also known as cefmetazole, is a third-generation cephalosporin antibiotic used in the treatment of various bacterial infections. It belongs to the beta-lactam class of antibiotics and functions by inhibiting cell wall synthesis in susceptible bacteria, ultimately leading to their death.
Pharmacological Profile
Cefmatilen has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria. Its mechanism of action involves binding to penicillin-binding proteins (PBPs) on the bacterial cell wall, which disrupts the cross-linking process necessary for bacterial growth and survival. As a result, the bacteria are unable to maintain their structural integrity and ultimately die. Cefmatilen has been shown to be effective against a wide range of pathogens, including Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa, among others. It is administered intravenously and typically given at intervals of every 6-8 hours in adults.
Cefmatilen side effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain or discomfort
- Stomach upset
- Dizziness
- Headache
- Fatigue
- Muscle weakness
- Joint or muscle pain
- Skin rash or itching
- Allergic reactions (such as hives, swelling of the face and lips, etc.)
- Rare but serious side effects include:
- Blood clotting problems
- Seizures (in rare cases)
- Mental/mood changes (e.g., anxiety, irritability, hallucinations)
- Rare but potentially life-threatening allergic reactions
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.