What is Cefodizime?
Cefodizime is a third-generation cephalosporin antibiotic used in the treatment of bacterial infections. It has a broad spectrum of activity, including against Gram-positive and Gram-negative bacteria, and is effective against both aerobic and anaerobic organisms. Cefodizime works by inhibiting cell wall synthesis in susceptible bacteria, ultimately leading to their death. The drug is administered intravenously and is usually reserved for serious or complicated infections that are not adequately controlled by other antibiotics.
What is Cefodizime used for?
Cefodizime, also known as CP45,419 or 1-Thio-7-[(1-carbamoyl-2-(Z)-thenyloxyimino)ethyl]methoxycephalosporan, is a third-generation cephalosporin antibiotic that belongs to the cephem class of β-lactam antibiotics. This medication was primarily developed by Schering Plough (now part of Merck & Co.) and was first reported in the 1980s for its antibacterial properties against Gram-positive and Gram-negative bacteria.
Cefodizime exhibits a broad spectrum of activity, with potent efficacy against various pathogens including Streptococcus pneumoniae, Escherichia coli, Klebsiella pneumoniae, and Haemophilus influenzae. This antibiotic works by inhibiting bacterial cell wall synthesis through the inhibition of penicillin-binding proteins (PBPs). Cefodizime’s chemical structure features a unique cephalosporin nucleus with an imine-containing side chain at position 7, which is thought to contribute to its high potency and stability profile. As such, it represented one of the newer generations of cephalosporins in clinical development during its time but never obtained major commercialization or use due to lack of sufficient market need.
Cefodizime side effects
- Allergic reactions (rash, hives, itching)
- Diarrhea
- Nausea and vomiting
- Abdominal pain or cramping
- Flatulence
- Bloating
- Headache
- Dizziness or lightheadedness
- Weakness or fatigue
- Increased risk of bleeding or bruising
- Abnormal heart rhythms
- Muscle weakness
- Seizures (rare)
- Behavioral changes (such as agitation, confusion, or hallucinations)
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.