What is Cefoperazone sodium?
Cefoperazone sodium is a third-generation cephalosporin antibiotic. It works by inhibiting bacterial cell wall synthesis, ultimately leading to the death of the bacterial cell. Cefoperazone sodium is used to treat various infections such as lower respiratory tract infections, urinary tract infections, and skin and soft tissue infections, caused by susceptible bacteria like Escherichia coli and Klebsiella pneumoniae. It is available in injectable form for intravenous or intramuscular administration.
What is Cefoperazone sodium used for?
Cefoperazone sodium, also known as Cefoperazone or Zosyn, is a third-generation cephalosporin antibiotic medication. It belongs to the class of broad-spectrum beta-lactam antibiotics and works by inhibiting cell wall synthesis in bacteria. This leads to the eventual death of bacterial cells.
Cefoperazone sodium has antimicrobial activity against a wide range of Gram-negative and some Gram-positive bacteria, making it effective in treating various infections such as pneumonia, septicemia, urinary tract infections, skin and soft tissue infections, and peritonitis. It is usually administered intravenously or orally in the treatment of bacterial infections, often in combination with other antibiotics to enhance its efficacy and reduce the risk of resistance.
In terms of pharmacokinetics, Cefoperazone sodium has a long half-life, allowing for once-daily dosing regimens without significant accumulation. Its absorption after oral administration is nearly complete, and it undergoes minimal metabolism before excretion in the urine as unchanged drug and conjugated metabolites.
Cefoperazone sodium side effects
• Diarrhea • Nausea and vomiting • Abdominal pain • Skin rash • Elevation in liver enzymes • Blood disorders (e.g., anemia, leukopenia) • Gastrointestinal bleeding • Allergic reactions • Thrombocytopenia • Hypersensitivity reactions (rare)
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