What is Cefoselis?
Cefoselis is a second-generation cephalosporin antibiotic. It was developed for the treatment of various bacterial infections, including urinary tract infections and skin infections. The mechanism of action involves inhibiting cell wall synthesis in susceptible bacteria. Cefoselis was found to be effective against certain Gram-positive and Gram-negative bacteria. However, due to concerns regarding its nephrotoxicity and hepatotoxicity potential, its use has been limited or discontinued in many countries.
What is Cefoselis used for?
Cefoselis is a cephamycin antibiotic that falls under the broader category of beta-lactam antibiotics, which also includes penicillins and cephalosporins. As a cephamycin, cefoselis has a similar chemical structure to other cephalosporin-type antibiotics but with specific modifications in its molecular framework. These structural differences can affect how cefoselis interacts with bacterial cell walls, leading to its antimicrobial properties.
Cephamycins like cefoselis work by inhibiting the synthesis of the bacterial cell wall, ultimately causing the bacteria’s death due to osmotic imbalance and rupture. This mechanism of action is unique among antibiotics since it directly targets an essential component of the bacterial cell structure—its wall. This specificity in action minimizes damage to human cells compared to other types of antibiotics that might interfere with protein synthesis or membrane function, although like all antibiotics, cefoselis can still have side effects and should be used judiciously under medical supervision.
Due to its antibiotic properties, cefoselis is typically indicated for the treatment of infections caused by certain susceptible bacteria. However, as a relatively lesser-known drug compared to other cephalosporins or cephamycins like cefotaxime or ceftazidime, detailed information about its usage and recommendations might not be widely disseminated unless specifically in contexts where it is being considered for use.
Cefoselis side effects
- Abdominal pain
- Allergic reactions (hives; itching; difficulty breathing; tightness in chest; swelling of face, lips, tongue, or throat)
- Blood count disorders (decreased red blood cells; decreased white blood cells; increased platelets)
- Diarrhea
- Hiccups
- Increased urinary frequency
- Muscle weakness
- Nausea
- Redness of face
- Stomach pain
- Taste perversion
- Vaginal discharge
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