Cefotaxime sodium

What is Cefotaxime sodium?

Cefotaxime sodium is a third-generation cephalosporin antibiotic. It works by interfering with the synthesis of bacterial cell walls, ultimately leading to the death of the bacteria. Cefotaxime sodium is used to treat various infections caused by susceptible bacteria, including pneumonia, meningitis, and urinary tract infections. The drug is typically administered intravenously or via injection, allowing it to reach high concentrations in the bloodstream and tissues quickly.

What is Cefotaxime sodium used for?

Cefotaxime sodium, also known as Cefotaxime or CTX, is a third-generation cephalosporin antibiotic. It belongs to the class of beta-lactam antibiotics that inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This results in the disruption of the bacterial cell wall structure and ultimately leads to cell death.

Cefotaxime sodium is a broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria. It has demonstrated efficacy against various pathogens, including those that cause pneumonia, sepsis, urinary tract infections (UTIs), meningitis, and other serious bacterial infections. This medication is usually administered intravenously in hospital settings to treat severe bacterial infections, particularly in patients who have not responded well to first or second-generation cephalosporins. As a member of the cephalosporin class, cefotaxime sodium’s mechanism of action relies on its ability to competitively inhibit PBP enzymes involved in bacterial cell wall formation.

Cefotaxime sodium side effects

  • Allergic reactions
  • Seizures
  • Confusion
  • Dizziness
  • Headache
  • Abnormalities in liver function tests
  • Increased risk of bleeding
  • Diarrhea
  • Vomiting
  • Nausea
  • Abdominal pain or cramping
  • Skin rash
  • Itching
  • Hives
  • Swelling of the face, lips, tongue, or throat
  • Stevens-Johnson syndrome (a rare but serious skin disorder)
  • Anaphylaxis (a severe, potentially life-threatening allergic reaction)

Disclaimer

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