What is Cefovecin sodium?
Cefovecin sodium is a long-acting injectable antibiotic that belongs to the cephalosporin class of drugs. It is used in veterinary medicine, specifically in cats and dogs, to treat skin infections and wounds caused by susceptible bacteria. The drug works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial death. Cefovecin sodium is administered via injection and has a duration of action that can last for up to 14 days in some species.
What is Cefovecin sodium used for?
Cefovecin sodium, also known as Convenia, is a cephalosporin antibiotic used in veterinary medicine for the treatment of various bacterial infections. It belongs to the second-generation cephalosporins class and works by inhibiting bacterial cell wall synthesis, ultimately leading to cell lysis and death.
Convenia cefovecin sodium is typically administered via intramuscular injection in dogs and cats to treat skin and soft tissue infections, respiratory tract infections, and urinary tract infections caused by susceptible bacteria. The drug has been shown to be effective against a range of Gram-positive and some Gram-negative bacteria, including Escherichia coli and Staphylococcus aureus. Cefovecin sodium’s mechanism of action involves binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, preventing cross-linking of peptidoglycan layers necessary for the structural integrity and growth of the bacteria. This leads to an imbalance in cellular functions, ultimately resulting in the death of the bacteria. Convenia cefovecin sodium is usually administered once a week for three weeks, providing long-lasting antibacterial activity while minimizing the risk of adverse effects associated with frequent dosing.
Cefovecin sodium side effects
• Allergic reactions • Anaphylaxis • Bleeding • Blood clots • Bone marrow suppression • Changes in blood counts (anemia, leukopenia, thrombocytopenia) • Decreased appetite • Diarrhea • Dry mouth • Eye problems (conjunctivitis, keratitis, uveitis) • Feeling of well-being decreased • Flushing • Gastrointestinal issues (abdominal pain, nausea, vomiting) • Increased heart rate • Injection site reactions (pain, redness, swelling) • Lymphadenopathy • Muscle weakness • Ocular toxicity • Pain • Postural hypotension • Skin problems (alopecia, dermatitis, pruritus) • Stunted growth • Taste disturbances • Tenderness
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