What is Cefprozil sulfate?
Cefprozil sulfate is a second-generation cephalosporin antibiotic that belongs to the class of beta-lactam antibiotics. It has a broad spectrum of activity against Gram-positive and some Gram-negative bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Cefprozil sulfate is available in various formulations for oral use, primarily to treat respiratory tract infections such as pneumonia, bronchitis, and sinusitis. It works by inhibiting bacterial cell wall synthesis, leading to the death of sensitive bacteria.
What is Cefprozil sulfate used for?
Cefprozil sulfite, also known as Cefprox, is a semi-synthetic second-generation cephalosporin antibiotic that belongs to the class of beta-lactam antibiotics. It was first approved by the US FDA in 1997 for the treatment of various bacterial infections in adults and children over six months of age. Cefprozil sulfite works by inhibiting the synthesis of the bacterial cell wall, ultimately leading to the death of the pathogenic bacteria.
Pharmacological Properties
Cefprozil sulfite has a broad spectrum of antimicrobial activity against both Gram-positive and Gram-negative bacteria, including those that cause respiratory tract infections (RTIs), skin and soft tissue infections (SSTIs), and urinary tract infections (UTIs). It is particularly effective against common pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Escherichia coli, and Klebsiella pneumoniae. The oral formulation of cefprozil sulfite has a bioavailability of approximately 95%, with peak plasma concentrations achieved within one to two hours after administration. Its elimination half-life is about three hours, making it suitable for twice-daily dosing regimens.
Cefprozil sulfate side effects
• Dizziness • Diarrhea • Nausea and vomiting • Abdominal pain or cramping • Allergic reactions (hives, itching, difficulty breathing) • Increased salivation • Vaginitis • Pharyngitis • Sinus infection • Tachycardia • Erythema multiforme (rash) • Stevens-Johnson syndrome • Angioedema
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