Cefquinome

What is Cefquinome?

Cefquinome is a third-generation cephalosporin antibiotic that belongs to the injectable cephalosporins class. It is used in veterinary medicine, specifically in cattle and pigs, to treat respiratory infections caused by susceptible bacteria such as Pasteurella multocida and Haemophilus parainfluenzae. Cefquinome exerts its antibacterial effects through the inhibition of bacterial cell wall synthesis.

What is Cefquinome used for?

Cefquinome is an injectable third-generation cephalosporin antibiotic that belongs to the cephem class of antibiotics. It has a broad spectrum of activity, effective against both Gram-positive and Gram-negative bacteria. Cefquinome is specifically designed for intramuscular administration in animals, particularly cattle, pigs, sheep, and goats, as an aid in controlling bacterial infections such as respiratory tract disease, enteritis, and mastitis.

The chemical structure of cefquinome consists of a beta-lactam ring that inhibits cell wall synthesis in bacteria, ultimately leading to the death of the pathogen. Its pharmacokinetic profile allows for efficient tissue distribution and a relatively long elimination half-life, ensuring prolonged antibiotic levels at the site of infection. This property makes it effective against a wide range of bacterial pathogens in animals, with minimal resistance development observed so far.

In veterinary practice, cefquinome is used as an adjunct therapy to control or prevent infections caused by susceptible bacteria. However, like all antibiotics, its effectiveness and safety should be carefully considered before use, especially considering factors such as dosage, duration of treatment, and potential for bacterial resistance development.

Cefquinome side effects

  • Local irritation at the injection site
  • Lethargy
  • Inappetence
  • Dilation of the pupils
  • Hives
  • Diarrhea
  • Vomiting
  • Muscle tremors
  • Slight decrease in the body temperature
  • Changes in behavior and activity level (such as changes in movement, aggression or excitement)
  • Ataxia
  • Lethargy

Disclaimer

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