What is Cefsulodin?
Cefsulodin is an injectable cephalosporin antibiotic used in the treatment of bacterial infections, including urinary tract infections and respiratory tract infections. It works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death. Cefsulodin has a spectrum of activity that includes many Gram-negative bacteria, but its use is often limited due to concerns about toxicity and availability.
What is Cefsulodin used for?
Cefsulodin, also known as cephalosporin antibiotic CF 1030 or Sulbactam Cefoperazone, is a third-generation cephalosporin antibiotic. It belongs to the class of beta-lactam antibiotics and operates by inhibiting cell wall synthesis in susceptible bacteria. The mechanism involves binding to penicillin-binding proteins (PBPs) present within bacterial cells, which are essential for the formation and maintenance of the bacterial cell envelope.
Pharmacological Profile: Cefsulodin has a broad spectrum of activity against both gram-positive and gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa. The drug is active against many beta-lactamase-producing strains that are resistant to other antibiotics. It has a unique structure featuring an extended side chain which allows for good stability in the presence of beta-lactamases.
Cefsulodin side effects
• Diarrhea • Rash • Abdominal pain • Vaginal candidiasis • Flatulence • Headache • Fever • Urinary frequency • Dizziness • Allergic reaction
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