What is Ceftibuten?
Ceftibuten is a third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections. It works by inhibiting bacterial cell wall formation, ultimately leading to the death of the bacteria. Ceftibuten has a broad spectrum of activity against both gram-positive and gram-negative bacteria. The drug is available in oral formulations for patient self-administration, typically taken twice daily with or without food.
What is Ceftibuten used for?
Ceftibuten, also known as Cefitek or Celestiat, is a third-generation cephalosporin antibiotic. It belongs to the β-lactam class of antibiotics and functions by inhibiting bacterial cell wall synthesis, ultimately leading to cell death. The chemical structure of ceftibuten features an unusual 1β-methylthio group at the C3 position, providing it with a distinct pharmacological profile compared to other cephalosporins.
Pharmacological Profile
Ceftibuten is characterized by its broad-spectrum antibacterial activity, which encompasses both Gram-positive and Gram-negative bacteria. It is particularly effective against respiratory tract infections, urinary tract infections, skin and soft tissue infections, as well as intra-abdominal infections caused by susceptible microorganisms. The pharmacokinetics of ceftibuten feature good oral bioavailability, allowing for once-daily dosing in many cases. Its relatively long half-life enables it to maintain therapeutic concentrations over an extended period, promoting convenient treatment regimens. As a result, ceftibuten has gained recognition as a valuable addition to the arsenal of antibiotics available for treating various bacterial infections.
Ceftibuten side effects
- Abdominal pain
- Allergic reactions (anaphylaxis)
- Diarrhea
- Fever
- Nausea and vomiting
- Rash
- Stomach upset
- Urine changes (darkened or concentrated urine)
- Vaginitis
- Increased liver enzymes
Disclaimer
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