Ceftriaxone disodium

What is Ceftriaxone disodium?

Ceftriaxone disodium, also known as Rocephin, is a third-generation cephalosporin antibiotic used to treat various bacterial infections. It works by inhibiting the synthesis of the bacterial cell wall, ultimately leading to the death of the bacteria. Ceftriaxone disodium is effective against a wide range of Gram-positive and Gram-negative bacteria, including those that cause pneumonia, meningitis, urinary tract infections, sepsis, and skin and soft tissue infections. It is typically administered intravenously and has a broad spectrum of activity, making it a valuable treatment option for serious bacterial infections.

What is Ceftriaxone disodium used for?

Ceftriaxone disodium, also known as Rocephin or Ceftriaxone sodium for injection, is a broad-spectrum cephalosporin antibiotic. It belongs to the third generation of cephalosporins and is primarily used in the treatment of various bacterial infections, including pneumonia, septicemia, meningitis, and urinary tract infections.

Ceftriaxone disodium works by inhibiting the synthesis of the cell wall of susceptible bacteria, leading to their death. It has a wide range of activity against both Gram-positive and Gram-negative bacteria, as well as some anaerobic organisms. The drug is administered intravenously or intramuscularly, with doses typically ranging from 50 mg to 2 grams per day, depending on the severity of the infection and the patient’s renal function.

The drug’s spectrum of activity includes organisms such as Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae, and Klebsiella pneumoniae, among others. Ceftriaxone disodium is also used in the treatment of Lyme disease caused by Borrelia burgdorferi. The drug’s efficacy has been established through various clinical studies, making it a first-line choice for several types of bacterial infections.

Ceftriaxone disodium side effects

• Allergic reactions • Anaphylaxis • Decreased platelet count (thrombocytopenia) • Increased bleeding tendency • Seizures • Central nervous system stimulation • Lactic acidosis • Hypotension • Tachycardia • Urticaria • Angioedema


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