What is Cefuroxime sodium hydrate?
Cefuroxime sodium is an injectable antibiotic belonging to the second-generation cephalosporin class. It functions by inhibiting bacterial cell wall synthesis, thereby preventing the growth and multiplication of susceptible bacteria. Cefuroxime sodium is used in the treatment of various bacterial infections including respiratory tract infections, urinary tract infections, and skin and soft tissue infections, among others.
What is Cefuroxime sodium hydrate used for?
Cefuroxime Sodium Hydrate, also known as Cefuroxime Injection or Zinacef, is a second-generation cephalosporin antibiotic. It belongs to the class of beta-lactam antibiotics that work by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial death. Cefuroxime sodium hydrate has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, and various species of Escherichia, Klebsiella, and Pseudomonas.
Cefuroxime sodium hydrate is typically administered intravenously or intramuscularly to treat a variety of bacterial infections such as urinary tract infections (UTIs), skin and soft tissue infections, pneumonia, and meningitis. The drug’s effectiveness and rapid action make it a valuable option for treating acute bacterial infections in both adults and pediatric patients. Cefuroxime sodium hydrate is usually well-tolerated but can cause side effects like hypersensitivity reactions, diarrhea, nausea, and renal dysfunction at high doses or prolonged use.
This antibiotic has been commercially available since the 1980s under various trade names such as Zinacef in Europe and Maxipime in North America. Despite advancements in newer cephalosporins with broader antibacterial coverage, cefuroxime sodium hydrate remains a trusted choice for healthcare providers to treat bacterial infections that are responsive to its spectrum of activity.
Cefuroxime sodium hydrate side effects
- Allergic reactions (rash, itching)
- Abnormal heartbeat
- Seizures
- Vaginal candidiasis
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Dizziness or drowsiness
- Headache
- Weakness
- Increased liver enzymes
- Blood clotting disorders
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