Clindamycin-benzoyl peroxide topical

What is Clindamycin-benzoyl peroxide topical?

Clindamycin-Benzoyl Peroxide Topical is a combination medication used to treat acne and other skin infections. It contains the antibiotic clindamycin, which helps kill bacteria that can cause acne, and benzoyl peroxide, an ingredient that reduces inflammation and kills bacteria as well. This topical treatment works by killing P. acnes bacteria and reducing inflammation in the pores of the skin, thereby helping to treat mild to moderate acne and other skin infections such as rosacea or impetigo.

What is Clindamycin-benzoyl peroxide topical used for?

Clindamycin-benzoyl peroxide topical is a combination medication that belongs to the class of antibiotics and antibacterial agents. It is primarily used in the treatment of moderate to severe acne, including pimples, redness, and inflammation. The medication works by combining two active ingredients: clindamycin and benzoyl peroxide.

Clindamycin, an antibiotic, targets bacteria that cause acne, such as Propionibacterium acnes (P. acnes), thereby reducing the growth of these bacteria. On the other hand, benzoyl peroxide, a keratolytic agent, helps to reduce inflammation and kills existing P. acnes bacteria by releasing oxygen free radicals. This combination therapy is effective in treating acne lesions, including comedones (blackheads) and papules (pimples), resulting in improved skin appearance.

Clindamycin-benzoyl peroxide topical side effects

  • Bacterial skin infections, especially with resistant organisms
  • Skin irritation, itching or redness
  • Dryness, scaling, and cracking of the skin around the anus (diaper rash)
  • Diarrhea or bloody stools
  • Vaginal infection in females
  • Rare but serious side effects:
    • Clostridioides difficile-associated diarrhea and colitis
    • Staphylococcal scalded skin syndrome
    • Stevens-Johnson syndrome/toxic epidermal necrolysis (a severe skin and mouth condition)
    • Allergic reactions, including hives or itching
    • Abnormal taste or smell
  • Infrequent side effects:
    • Burning or stinging sensation when the medication is applied to the skin

Disclaimer

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