Clonidine-guanfacine

What is Clonidine-guanfacine?

Apadaz (clonidine-guanfacine) is an extended-release, fixed-dose combination tablet containing clonidine hydrochloride and guanfacine extended release. It is used as a monotherapy for the treatment of attention deficit hyperactivity disorder (ADHD). The combination of these two agents in one formulation may provide a unique mechanism of action that addresses multiple pathways involved in ADHD symptomatology, thereby potentially offering improved efficacy in managing symptoms compared to either agent alone.

What is Clonidine-guanfacine used for?

KINTIQ (extended-release capsules containing clonidine and guanfacine)

Kintiq is a central nervous system stimulant that combines the pharmacologically active components of extended-release clonidine hydrochloride, 0.2 mg per milliliter, and guanfacine extended-release tablets, 1 mg per milliliter. This dual-action medication is primarily used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged six years and older who have a proven diagnosis of ADHD.

In Kintiq, clonidine helps to manage symptoms of ADHD such as hyperactivity by reducing impulsivity and aggression in children with this condition. Guanfacine, on the other hand, works synergistically with clonidine to help minimize excess motor activity associated with ADHD while maintaining emotional stability in these patients. Overall, Kintiq is an innovative medication that effectively supports treatment efforts for individuals suffering from ADHD.

Clonidine-guanfacine side effects

• Dizziness • Headache • Fatigue • Insomnia • Nausea • Vomiting • Dry mouth • Constipation • Abdominal pain • Increased heart rate • Decreased heart rate • Hypotension (low blood pressure) • Syncope (fainting) • Confusion • Drowsiness • Sedation • Hallucinations • Memory impairment • Anxiety • Depression • Irritability • Aggression


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