What is Colesevelam?
Colesevelam, also known as Welchol, is an oral antihyperlipidemic medication used to lower cholesterol levels in the blood. It belongs to the class of bile acid sequestrants and works by binding to bile acids in the intestines, preventing their reabsorption into the bloodstream. This leads to an increase in the production of bile acids from cholesterol in the liver, which in turn decreases the amount of cholesterol available for release into the blood. Colesevelam is used alone or with other medications to treat high cholesterol levels and is typically taken once daily.
What is Colesevelam used for?
Colesevelam, also known as Welchol, is an oral medication used in the management of high cholesterol (hypercholesterolemia). It belongs to a class of drugs called bile acid sequestrants, which work by binding to and removing bile acids from the bloodstream. This process helps to reduce the amount of bile acids produced by the liver, resulting in increased removal of low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol.
By lowering LDL cholesterol levels, colesevelam can help reduce the risk of cardiovascular events such as heart attacks and strokes. It is typically used in combination with a statin or other lipid-lowering medications for patients who require significant reductions in LDL cholesterol levels. The medication is available in both tablet and powder forms, making it convenient to take as directed by a healthcare professional. Overall, colesevelam provides an effective treatment option for individuals struggling with high cholesterol and associated cardiovascular risks.
Colesevelam’s mechanism of action involves the sequestration of bile acids, which leads to an increase in the production of new cholesterol in the liver. This process effectively reduces the amount of LDL cholesterol present in the bloodstream. The medication is primarily used in adults who have elevated LDL cholesterol levels and are at risk for cardiovascular events. When taken as directed, colesevelam has been shown to be a valuable adjunct therapy for patients requiring additional lipid-lowering support.
Colesevelam side effects
- Abdominal pain
- Altitude sickness
- Blood sugar decreased
- Chest discomfort
- Constipation
- Dizziness
- Fatigue
- Increased risk of low blood sugar
- Lower back pain
- Muscle cramps
- Rash
- Skin hyperpigmentation
- Swelling in hands and feet
- Thirst
- Vomiting
Disclaimer
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