What is Colestipol?
Colestipol is an anticholesteremic agent that works by binding bile acids in the intestine, thereby reducing their reabsorption and resulting in increased excretion. This action decreases the amount of cholesterol produced in the liver. Colestipol belongs to a class of drugs known as bile acid sequestrants and is used to lower serum cholesterol levels, primarily in patients with primary hypercholesterolemia. It is available orally in various forms and dosages for administration.
What is Colestipol used for?
Introducing Colestipol
Colestipol, also known as Colestipol hydrochloride or Colestid, is an oral medication primarily used in the management of high cholesterol levels (hypercholesterolemia). This bile acid sequestrant belongs to a class of medications that work by binding to bile acids in the gastrointestinal tract and preventing their reabsorption into the bloodstream. As a result, the liver is stimulated to produce more bile acids from cholesterol, thereby lowering the overall cholesterol levels.
Mechanism of Action and Uses
Colestipol works by forming insoluble complexes with bile acids, which are then excreted in the feces. This action decreases the amount of cholesterol available for incorporation into very-low-density lipoprotein (VLDL) particles and subsequently released into the bloodstream. By reducing circulating cholesterol levels, colestipol helps to lower the risk of cardiovascular disease in patients with high cholesterol.
Colestipol is often prescribed as an adjunctive therapy in conjunction with dietary changes to manage elevated low-density lipoprotein (LDL) cholesterol, triglycerides, and apolipoproteins. The medication’s effects on high-density lipoprotein (HDL) or “good” cholesterol levels are generally minimal. Colestipol has been used for decades and remains a valuable treatment option for patients with primary hypercholesterolemia.
Colestipol side effects
- Abdominal cramps
- Bloating
- Breast tenderness
- Chills
- Constipation
- Diarrhea
- Fatigue
- Feeling of impending doom (Rare)
- Gallbladder disease
- Gas
- Headache
- Joint pain
- Menstrual changes
- Muscle weakness
- Nausea
- Pain in extremities
- Stomach upset
- Swelling in hands, feet, or ankles
- Vaginal discharge
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.