What is Dalcetrapib?
Dalcetrapib is an investigational agent that belongs to the class of drugs known as cholesteryl ester transfer protein (CETP) inhibitors. It was being developed by Merck & Co., Inc. for the potential treatment and prevention of cardiovascular diseases, specifically high cholesterol levels and atherosclerosis. Dalcetrapib was designed to work by inhibiting the action of CETP, which plays a role in the regulation of lipid metabolism.
What is Dalcetrapib used for?
Name: Dalcetrapib Class: Antiatherosclerotic agent; CETP inhibitor
Dalcetrapib, also known by its research code RT-000216, is an experimental drug that was being investigated for its potential to slow the progression of atherosclerosis. Atherosclerosis, often referred to as “hardening of the arteries,” occurs when plaque builds up inside the blood vessels, leading to blockages and potentially resulting in heart attacks or strokes. Dalcetrapib worked by inhibiting the activity of cholesteryl ester transfer protein (CETP), which plays a crucial role in lipid metabolism and transport within the body.
As a CETP inhibitor, dalcetrapib aimed to increase levels of high-density lipoprotein cholesterol (HDL-C) or “good” cholesterol while decreasing low-density lipoprotein cholesterol (LDL-C) or “bad” cholesterol. This dual action is believed to help prevent the formation of atherosclerotic plaques and reduce cardiovascular risk in individuals. Although promising, dalcetrapib has faced challenges and setbacks during clinical trials; its potential efficacy and safety profile remain under review as part of ongoing research efforts.
Dalcetrapib side effects
- Increased risk of cardiovascular events such as heart attacks, strokes
- Muscle pain or weakness
- Fatigue
- Joint pain
- Headache
- Back pain
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Changes in blood pressure
- Swelling in legs and feet (edema)
- Increased urination
- Flu-like symptoms
- Rash
- Itching or hives
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.