What is Delamanid?
Delamanid is an antimicrobial medication used to treat tuberculosis (TB), particularly in patients who are resistant to or intolerant of other TB drugs. It works by inhibiting the enzyme mycobacterial protein tyrosine phosphatase, which is essential for Mycobacterium tuberculosis growth and survival. Delamanid has shown effectiveness when used as part of a combination therapy regimen for treating pulmonary TB.
What is Delamanid used for?
Delamanid, also known as Deltyba in some countries, is an antitubercular medication used in the treatment of tuberculosis (TB). It belongs to a class of drugs called diarylquinones. TB is a potentially life-threatening infectious disease caused by the bacterium Mycobacterium tuberculosis that primarily affects the lungs but can also affect other parts of the body.
Delamanid was first approved for use in Europe in 2014 and later in the United States and other countries. It works by inhibiting the growth of M. tuberculosis, thereby allowing the body’s natural defense mechanisms to kill the bacteria. The drug has been particularly useful in treating multidrug-resistant TB (MDR-TB), a form of TB that does not respond to standard first-line antibiotics. Delamanid is typically used in combination with other antitubercular medications as part of a comprehensive treatment regimen for TB patients, often in conjunction with the World Health Organization’s recommended MDR-TB treatment protocols. Its unique mechanism of action and safety profile make it an important addition to the arsenal against this complex and challenging disease.
Delamanid side effects
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
- Headache
- Fatigue
- Dizziness
- Weakness
- Rash
- Itching
- Insomnia
- Dry mouth
- Increased heart rate
- Muscle pain
- Decreased appetite
Disclaimer
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