What is Doxazosin-hydrochlorothiazide?
Doxazosin-Hydrochlorothiazide, commonly known as Doxazosin and HCTZ combination, is a medication used to treat hypertension (high blood pressure) and benign prostatic hyperplasia (BPH). It combines the vasodilator doxazosin with hydrochlorothiazide, a thiazide diuretic. The two ingredients work together to relax blood vessels, allowing for better blood flow and lower blood pressure, while also promoting urination by reducing urine retention. This combination is used primarily in patients who experience both high blood pressure and urinary difficulties due to BPH symptoms.
What is Doxazosin-hydrochlorothiazide used for?
Doxazosin-hydrochlorothiazide, also known as Cardura HCT, is a prescription medication that combines the alpha-1 adrenergic blocker doxazosin with the thiazide diuretic hydrochlorothiazide. This combination therapy is used to treat high blood pressure (hypertension) in adults.
The addition of doxazosin to hydrochlorothiazide allows for a dual mechanism of action, reducing blood pressure through both vasodilation and increased urine production. Doxazosin works by relaxing the muscles in the blood vessel walls, causing them to widen and allowing blood to flow more easily. Hydrochlorothiazide, on the other hand, promotes diuresis, helping the body to eliminate excess fluids and electrolytes that contribute to high blood pressure.
The use of a combination therapy like doxazosin-hydrochlorothiazide allows for a single tablet formulation that can be taken once daily, which may improve patient compliance compared to separate tablets. However, as with any medication, it is essential to follow the prescribed dosing and administration instructions carefully to achieve optimal blood pressure control while minimizing potential side effects.
Doxazosin-hydrochlorothiazide side effects
- Allergic reactions
- Angioedema
- Ankle swelling (peripheral edema)
- Decreased libido
- Dizziness
- Dry mouth
- Ejaculation failure
- Erectile dysfunction
- Fatigue
- Headache
- Hives
- Increased heart rate
- Itching
- Nausea
- Postural hypotension
- Rash
- Sleepiness
- Sweating
- Taste changes
- Tiredness
- Urticaria (hives)
- Vaginal discharge
- Weight loss
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