What is Eravacycline?
Eravacycline is a broad-spectrum antibacterial agent, specifically a fluoroquinolone antibiotic. It works by inhibiting the bacterial enzyme DNA gyrase and topoisomerase IV, essential for bacterial DNA replication and transcription. Eravacycline has been shown to be effective against various Gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae, and Enterobacter spp., as well as certain Gram-positive organisms.
What is Eravacycline used for?
Eravacycline is a tetracycline antibiotic, specifically designed for the treatment of bacterial infections. As a member of the tetracycline class, eravacycline has broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. This unique characteristic makes it an effective option in treating various types of bacterial infections that are resistant to other antibiotics.
The mechanism of action of eravacycline involves inhibiting protein synthesis by binding to the 30S subunit of the bacterial ribosome, thereby preventing the production of essential proteins required for bacterial growth and reproduction. This results in the death of the bacteria, effectively treating the infection. The pharmacokinetics of eravacycline have been optimized to allow once-daily dosing, which can improve patient compliance and adherence.
Clinical Use
Eravacycline has been approved by regulatory agencies, including the U.S. Food and Drug Administration (FDA), for the treatment of certain types of infections. These include complicated urinary tract infections (cUTIs) caused by susceptible Gram-positive and Gram-negative bacteria. The drug’s broad-spectrum activity makes it a valuable option in managing complex infections where multiple pathogens are involved.
Important Safety Information
As with any antibiotic, there is potential for eravacycline to cause side effects or interact with other medications. Patients using this medication should be informed of the risk of gastrointestinal disturbances, including diarrhea and nausea. Rare but serious allergic reactions have also been reported in some patients receiving eravacycline.
Eravacycline side effects
- Abdominal pain
- Diarrhea
- Infusion site reaction
- Nausea
- Vomiting
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.