What is Ertugliflozin?
Ertugliflozin is an oral anti-diabetic medication, a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by preventing the kidneys from reabsorbing glucose back into the bloodstream, allowing excess sugar to be excreted in the urine, thereby lowering blood glucose levels in patients with type 2 diabetes mellitus.
What is Ertugliflozin used for?
Ertugliflozin, also known as Steglatro, is an oral medication used in the treatment of type 2 diabetes. It belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT-2) inhibitors. As such, Ertugliflozin works by inhibiting the reabsorption of glucose from the filtrate in the proximal convoluted tubule of the kidneys, resulting in its excretion in the urine.
The primary mechanism of action of Ertugliflozin involves blocking the SGLT-2 receptors in the kidneys, thereby reducing the reabsorption of glucose back into the bloodstream. This leads to a decrease in blood sugar levels. By doing so, Ertugliflozin helps patients with type 2 diabetes control their blood glucose levels more effectively and manage their condition over time. In clinical trials, the drug has been shown to demonstrate efficacy in reducing hemoglobin A1c (HbA1c) levels, which is a key indicator of glycemic control in diabetic patients.
Ertugliflozin side effects
• Increased risk of diabetic ketoacidosis • Genital area infections (yeast infections, genital candidiasis) • Increased urination • Low blood sugar • Skin rash • Diarrhea or stomach discomfort • Nausea or vomiting • Back pain • Headache
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