What is Esmolol?
Esmolol is a beta-1 adrenergic receptor blocker (beta-blocker) used intravenously in emergency situations, such as unstable angina, myocardial infarction, and supraventricular tachycardia. It rapidly decreases heart rate and blood pressure by inhibiting the effects of epinephrine on the heart. Esmolol has a short duration of action, typically lasting 10-20 minutes, which makes it useful in acute settings where control over cardiac function is needed for a limited period.
What is Esmolol used for?
Esmolol is an intravenous beta-1 selective adrenergic receptor blocker used in the management of supraventricular tachycardia (SVT), atrial fibrillation, and perioperative hypertension. It has a very short duration of action, typically lasting between 9 to 12 minutes.
Esmolol works by competitively blocking beta-1 receptors on cardiac tissue, thereby reducing the force and rate of heart contractions. This effect leads to decreased heart rate and blood pressure in patients experiencing SVT or hypertension. Esmolol is often used as a rapidly acting agent for acute management of these conditions, providing temporary relief until more definitive treatment can be implemented. As a selective beta-1 blocker, esmolol does not have significant effects on other beta-receptor subtypes, minimizing potential risks such as vasodilation or bronchodilatation commonly seen with non-selective blockers like propranolol.
Esmolol side effects
• Tachycardia • Hypotension • Chest pain • Headache • Nausea and vomiting • Diarrhea • Abdominal cramps • Back pain • Flu-like symptoms • Dizziness • Weakness • Shortness of breath • Wheezing
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