What is Fenobibrate?
Fenofibric acid (Fenobamate is incorrect, I’m assuming Fenobibrate was intended) is a medication used to treat high cholesterol and triglyceride levels. It belongs to the class of drugs known as fibrates and works by reducing the amount of lipids in the blood. Specifically, fenofibric acid helps decrease low-density lipoprotein (LDL) or “bad” cholesterol levels, which can contribute to plaque buildup in arteries and increase the risk of cardiovascular events such as heart attacks and strokes.
What is Fenobibrate used for?
Fenofibrate is a medication used to treat high cholesterol and triglyceride levels in the blood, which are risk factors for heart disease. It belongs to the class of medications known as fibric acid derivatives or fibrates. Fenofibrate works by activating an enzyme called peroxisome proliferator-activated receptor-alpha (PPAR-alpha), which helps regulate the levels of cholesterol and triglycerides in the body.
Fenofibrate is available in various forms, including immediate-release tablets, extended-release capsules, and oral solution. It is often prescribed for patients who have not achieved adequate reductions in cholesterol or triglyceride levels with diet and exercise alone, or as an adjunct to other lipid-lowering therapies like statins. Common side effects of fenofibrate include abdominal pain, nausea, vomiting, and changes in liver enzymes.
Common Uses:
Fenofibrate is indicated for the treatment of:
- Primary hypercholesterolemia (high cholesterol) and mixed dyslipidemia
- Hypertriglyceridemia (elevated triglyceride levels)
- High-density lipoprotein (HDL) or “good” cholesterol deficiency
Dosing:
The typical starting dose for fenofibrate is 54 mg once daily, which may be adjusted based on the patient’s response to therapy.
Fenobibrate side effects
• Abdominal pain • Anorexia • Arterial thrombosis • Bilirubinemia • Cholelithiasis • Colitis • Diarrhea • Dyspepsia • Elevated liver enzymes • Flatulence • Gastrointestinal disorder • Increased risk of bleeding • Liver damage • Muscle weakness • Pancreatitis • Rash • Steatorrhea • Urinary frequency
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