Aliskiren

What is Aliskiren? Aliskiren is a direct renin inhibitor used in the treatment of hypertension. It works by blocking the action of the enzyme renin, which plays a key role in regulating blood pressure through the regulation of angiotensin and aldosterone levels. Aliskiren has been shown to reduce systolic and diastolic blood pressure in patients with essential hypertension. What is Aliskiren used for? Aliskiren, also known as Tekturna, is a direct renin inhibitor that was approved by the US FDA in 2007 for the treatment of hypertension....

October 3, 2024 · 2 min · Michael Henderson

Aliskiren-hydrochlorothiazide

What is Aliskiren-hydrochlorothiazide? Aliskiren (sold under the brand name Rasilez among others) is a medication used in conjunction with other medications to treat high blood pressure. It works by blocking the action of angiotensin II, a naturally occurring hormone that constricts blood vessels. Aliskiren is an oral direct renin inhibitor and has not been approved for use as a standalone treatment in many countries due to concerns about its safety profile....

October 3, 2024 · 3 min · Michael Henderson

Alogliptin

What is Alogliptin? Alogliptin is an oral antidiabetic agent that belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by inhibiting the enzyme DPP-4, which breaks down incretin hormones GLP-1 and GIP in the gastrointestinal tract. By preserving or enhancing the levels of these hormones, Alogliptin increases insulin secretion in response to meals and decreases glucagon levels in a glucose-dependent manner, thereby lowering blood glucose concentrations. What is Alogliptin used for?...

October 3, 2024 · 2 min · Michael Henderson

Alogliptin-metformin

What is Alogliptin-metformin? Alogliptin-metformin, also known as Xigduo XR, is a fixed-dose combination medication. Alogliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors that helps regulate blood sugar levels by inhibiting the enzyme DPP-4. Metformin, on the other hand, works as a biguanide to decrease glucose production in the liver and increase insulin sensitivity. This combination medication is used in the treatment of type 2 diabetes mellitus (T2DM), helping patients control their blood sugar levels....

October 3, 2024 · 3 min · Michael Henderson

Alpha-linolenic acid (ALA)

What is Alpha-linolenic acid (ALA)? Omega-3 fatty acid supplement, Alpha-linolenic acid (ALA) is an essential fatty acid derived from plant sources such as flaxseed oil and canola oil. It plays a crucial role in the production of omega-3 fatty acids EPA and DHA, which are vital for heart health, brain function, and may help alleviate symptoms of depression, ADHD, and other conditions. ALA is available over-the-counter (OTC) in various forms including capsules, softgels, and oil concentrates....

October 3, 2024 · 2 min · Michael Henderson