What is Eprosartan-amlodipine?
Eprosartan-amlodipine, also known as Eprovan-AMT, is a fixed-dose combination medication containing the angiotensin II receptor antagonist eprosartan and the calcium channel blocker amlodipine. It is used to treat high blood pressure in adults, helping to lower blood pressure and reduce the risk of cardiovascular events such as heart attacks and strokes. Eprosartan-amlodipine works by relaxing blood vessels, allowing blood to flow more easily, which in turn reduces blood pressure and strain on the heart.
What is Eprosartan-amlodipine used for?
Eprosartan-amlodipine, also known as a fixed-dose combination of eprosartan and amlodipine, is an antihypertensive medication used in the treatment of high blood pressure (hypertension) and certain cases of heart failure. This combination therapy combines two distinct classes of drugs: angiotensin II receptor antagonists (ARBs), represented by eprosartan, with calcium channel blockers (CCBs), represented by amlodipine.
The combination of eprosartan and amlodipine offers a dual-action approach to lowering blood pressure. Eprosartan works as an ARB by selectively blocking the angiotensin II receptor, preventing vasoconstriction and reducing peripheral resistance. Amlodipine, on the other hand, acts as a CCB that inhibits the influx of calcium ions into cardiac and vascular smooth muscle cells, leading to vasodilation. The synergy between these mechanisms contributes to significant reductions in blood pressure.
Eprosartan-amlodipine side effects
- Dizziness
- Headache
- Fatigue
- Edema (swelling) of legs and feet
- Nausea and vomiting
- Diarrhea or stomach pain
- Muscle cramps
- Coughing up blood (hemoptysis)
- Chest pain or pressure (angina)
- High potassium levels in the blood (hyperkalemia)
- Changes in kidney function
- Increased heart rate (tachycardia)
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