What is Fenofibrate Micronized?
Fenofibrate Micronized is an antilipidemic medication used to lower triglyceride levels and improve high-density lipoprotein (HDL) cholesterol in patients with primary hyperlipidemia or mixed dyslipidemia. It works by inhibiting the production of very-low-density lipoproteins (VLDL) and increasing the breakdown of triglycerides in the liver. This medication is available in various formulations, including tablets, capsules, and injectable forms.
What is Fenofibrate Micronized used for?
Fenofibrate Micronized is an oral antilipemic agent that belongs to the class of fibric acid derivatives. It is a medication used in the management and treatment of adult patients with hypertriglyceridemia, mixed dyslipidemia, and primary hypercholesterolemia (elevated cholesterol levels). Fenofibrate Micronized works by activating the peroxisome proliferator-activated receptor-alpha (PPAR-alpha), which regulates the expression of genes involved in lipid metabolism. This leads to increased lipolysis and reduced apolipoprotein C-II production, resulting in decreased triglyceride and low-density lipoprotein (LDL) cholesterol levels.
Fenofibrate Micronized is also used in combination with other medications for the treatment of patients with mixed dyslipidemia or hypercholesterolemia who have not achieved adequate response to diet alone. It can be used in both primary prevention, where the goal is to reduce the risk of cardiovascular disease in patients without prior myocardial infarction (heart attack), and secondary prevention, where the goal is to prevent recurrent heart attacks in patients with a history of such events. However, as with any medication, its use should be weighed against potential side effects and contraindications.
Fenofibrate Micronized side effects
- Abdominal pain
- Back pain
- Bronchitis
- Constipation
- Coughing up mucus
- Dizziness
- Fatigue
- Headache
- Increased risk of gallstones
- Muscle aches
- Nausea
- Rash
- Stomach upset
- Unusual taste
Rare side effects include:
- Allergic reaction
- Bone pain
- Decreased appetite
- Fever
- Joint pain
- Muscle weakness
- Seizure
- Sore throat
- Swollen lymph nodes
- Vision problems
Disclaimer
The content on this website is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. The information provided here is based on general research and may not apply to individual circumstances. We do not guarantee the accuracy or completeness of any content on this website. Always consult with a healthcare professional before making any changes to your medication or health routine.