What is Fenofibric acid?
Fenofibric Acid is an antihyperlipidemic medication used to treat high cholesterol and triglyceride levels, thereby reducing the risk of cardiovascular disease. It works by inhibiting the enzyme lipoprotein lipase lipolytic enzyme, which breaks down triglycerides in the bloodstream. This leads to decreased levels of very low-density lipoprotein (VLDL) and triglycerides, as well as increased high-density lipoprotein (HDL) or “good” cholesterol.
What is Fenofibric acid used for?
Fenofibric acid, also known as fenofibrate, is a medication used to lower high cholesterol and triglyceride levels in the blood. It belongs to a class of drugs called fibrates, which work by activating a specific protein called peroxisome proliferator-activated receptor-alpha (PPAR-alpha). This activation leads to increased lipolysis (fat breakdown) and decreased synthesis of very-low-density lipoprotein (VLDL), a type of cholesterol.
Fenofibric acid is primarily used to treat hypertriglyceridemia, or high levels of triglycerides in the blood. It is also effective in reducing low-density lipoprotein (LDL) cholesterol and apolipoprotein B-100 levels, which are associated with an increased risk of cardiovascular disease. The medication is available in various formulations, including capsules, tablets, and oral solutions. As a fibrate, fenofibric acid is metabolized by the liver and excreted primarily through the bile and feces. Common dosage regimens involve daily or weekly administration, depending on the specific product and patient requirements.
Fenofibric acid side effects
• Abdominal pain • Asthenia • Constipation • Dizziness • Elevated liver enzymes • Headache • Increased CPK levels • Muscle cramps • Nausea • Rash • Unpleasant taste or smell • Weakness
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